In case you haven’t seen this already elsewhere, here’s a slice of a fantastic article in The Guardian. The article is titled “The dead end of animal research” and subtitled: “Despite persistent lobbying for animal testing, the evidence shows it is of little use in developing medicines for humans.” Here is a section:
My answer to the question “If a treatment works on rodents, will it cure us?” is “probably not, based on the weight of evidence to date”. Cancer is a good example: former director of the US National Cancer Institute, Dr Richard Klausner lamented: “We have cured mice of cancer for decades, and it simply didn’t work in humans.” Aids is another: while at least 80 vaccines work in animals, all 80 have failed in human trials. Similarly, every one of more than 150 stroke treatments successful in animals has failed in human testing. A study in the British Medical Journal (pdf) found that animal tests accurately predict human response less than 50% of the time.